HCSGD entry for SPC24
1. General information
| Official gene symbol | SPC24 |
|---|---|
| Entrez ID | 147841 |
| Gene full name | SPC24, NDC80 kinetochore complex component |
| Other gene symbols | SPBC24 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000777 | Condensed chromosome kinetochore | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0031262 | Ndc80 complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9480930360 | 0.0002763231 | 0.9999902473 | 0.0305592437 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5460228841 |
| GSE13712_SHEAR | Up | 0.1310629272 |
| GSE13712_STATIC | Down | -0.2171898798 |
| GSE19018 | Up | 0.2559258972 |
| GSE19899_A1 | Down | -0.5156336568 |
| GSE19899_A2 | Down | -3.3232093844 |
| PubMed_21979375_A1 | Down | -3.0682798581 |
| PubMed_21979375_A2 | Down | -3.0001516432 |
| GSE35957 | Down | -0.8981291436 |
| GSE36640 | Down | -5.0135977292 |
| GSE54402 | Down | -0.9690394992 |
| GSE9593 | Down | -0.9481380806 |
| GSE43922 | Down | -1.7284610080 |
| GSE24585 | Down | -0.1503018411 |
| GSE37065 | Down | -0.1681548429 |
| GSE28863_A1 | Down | -0.3181309574 |
| GSE28863_A2 | Up | 0.3606191001 |
| GSE28863_A3 | Up | 0.0896117575 |
| GSE28863_A4 | Up | 0.2774915556 |
| GSE48662 | Down | -0.2909108803 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023587 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040615 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
