HCSGD entry for CSTB
1. General information
| Official gene symbol | CSTB |
|---|---|
| Entrez ID | 1476 |
| Gene full name | cystatin B (stefin B) |
| Other gene symbols | CST6 EPM1 EPM1A PME STFB ULD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002020 | Protease binding | IPI | molecular_function |
| GO:0004866 | Endopeptidase inhibitor activity | TAS | molecular_function |
| GO:0004869 | Cysteine-type endopeptidase inhibitor activity | IDA | molecular_function |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0008344 | Adult locomotory behavior | IEA | biological_process |
| GO:0010466 | Negative regulation of peptidase activity | IDA | biological_process |
| GO:0010951 | Negative regulation of endopeptidase activity | IDA TAS | biological_process |
| GO:0042981 | Regulation of apoptotic process | IEA | biological_process |
| GO:0052548 | Regulation of endopeptidase activity | IDA TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0677048098 | 0.9613441321 | 0.5596405897 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4801371583 |
| GSE13712_SHEAR | Up | 0.0478400772 |
| GSE13712_STATIC | Up | 0.2460525955 |
| GSE19018 | Down | -0.2524109392 |
| GSE19899_A1 | Up | 0.0901299524 |
| GSE19899_A2 | Up | 0.3342841166 |
| PubMed_21979375_A1 | Down | -0.3031841616 |
| PubMed_21979375_A2 | Up | 0.0648894667 |
| GSE35957 | Up | 0.2555571141 |
| GSE36640 | Up | 0.2539667863 |
| GSE54402 | Up | 0.1508086877 |
| GSE9593 | Up | 0.6924507197 |
| GSE43922 | Up | 0.1352630260 |
| GSE24585 | Up | 0.3293467482 |
| GSE37065 | Up | 0.1857114549 |
| GSE28863_A1 | Down | -0.1482208402 |
| GSE28863_A2 | Down | -0.0000474401 |
| GSE28863_A3 | Down | -0.1344526419 |
| GSE28863_A4 | Up | 0.3304007925 |
| GSE48662 | Down | -0.1229598989 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-5p | MIMAT0004949 | MIRT037284 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038056 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-2-3p | MIMAT0004603 | MIRT038631 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
