HCSGD entry for CSTA

1. General information

Official gene symbolCSTA
Entrez ID1475
Gene full namecystatin A (stefin A)
Other gene symbolsAREI STF1 STFA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001533Cornified envelopeIDAcellular_component
GO:0002020Protease bindingIPImolecular_function
GO:0004869Cysteine-type endopeptidase inhibitor activityIDA IEAmolecular_function
GO:0005198Structural molecule activityIDAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0010466Negative regulation of peptidase activityIDAbiological_process
GO:0010951Negative regulation of endopeptidase activityIDAbiological_process
GO:0016337Cell-cell adhesionIMPbiological_process
GO:0018149Peptide cross-linkingIDAbiological_process
GO:0030216Keratinocyte differentiationIDAbiological_process
GO:0030674Protein binding, bridgingIDAmolecular_function
GO:0052548Regulation of endopeptidase activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00356606510.91667300250.16183172411.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.9179681582
GSE13712_SHEARUp0.2404623807
GSE13712_STATICUp0.0603321665
GSE19018Down-0.2713169218
GSE19899_A1Up0.5406745970
GSE19899_A2Up2.2415831430
PubMed_21979375_A1Up2.5966484015
PubMed_21979375_A2Up1.4731927271
GSE35957Down-0.2618847508
GSE36640Down-0.0672312619
GSE54402Down-0.2758142289
GSE9593Up0.5729683165
GSE43922Up0.0141269957
GSE24585Up0.1826373610
GSE37065Down-0.1271770633
GSE28863_A1Up0.2310364642
GSE28863_A2Up0.0188917065
GSE28863_A3Up0.2895873795
GSE28863_A4Up0.0505051374
GSE48662Up0.9193920811

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.