HCSGD entry for CST6
1. General information
| Official gene symbol | CST6 |
|---|---|
| Entrez ID | 1474 |
| Gene full name | cystatin E/M |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001533 | Cornified envelope | IEA | cellular_component |
| GO:0004869 | Cysteine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0008544 | Epidermis development | IEA | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0010951 | Negative regulation of endopeptidase activity | TAS | biological_process |
| GO:0052548 | Regulation of endopeptidase activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0851304054 | 0.8915427377 | 0.6135589814 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0598865335 |
| GSE13712_SHEAR | Up | 0.1128616645 |
| GSE13712_STATIC | Up | 0.2020936774 |
| GSE19018 | Down | -0.0290101036 |
| GSE19899_A1 | Up | 0.0854496520 |
| GSE19899_A2 | Up | 0.0724228812 |
| PubMed_21979375_A1 | Down | -0.2257240312 |
| PubMed_21979375_A2 | Up | 0.0600600291 |
| GSE35957 | Up | 0.3793635679 |
| GSE36640 | Up | 0.2179521355 |
| GSE54402 | Down | -0.0259192102 |
| GSE9593 | Up | 0.1505748152 |
| GSE43922 | Up | 0.1471355151 |
| GSE24585 | Down | -0.0221787924 |
| GSE37065 | Down | -0.2124805163 |
| GSE28863_A1 | Up | 0.0377575037 |
| GSE28863_A2 | Down | -0.2243364452 |
| GSE28863_A3 | Up | 0.2399496436 |
| GSE28863_A4 | Up | 0.5861927406 |
| GSE48662 | Up | 0.9597210727 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018413 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
