HCSGD entry for CST2
1. General information
| Official gene symbol | CST2 |
|---|---|
| Entrez ID | 1470 |
| Gene full name | cystatin SA |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004869 | Cysteine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0010951 | Negative regulation of endopeptidase activity | TAS | biological_process |
| GO:0052548 | Regulation of endopeptidase activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0009021200 | 0.9494776300 | 0.0824468750 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2791722137 |
| GSE13712_SHEAR | Down | -0.2932726300 |
| GSE13712_STATIC | Down | -0.5775314814 |
| GSE19018 | Up | 0.2349057879 |
| GSE19899_A1 | Up | 2.7727274331 |
| GSE19899_A2 | Up | 2.8672647250 |
| PubMed_21979375_A1 | Up | 1.8124112252 |
| PubMed_21979375_A2 | Up | 5.0071394022 |
| GSE35957 | Down | -0.0701668089 |
| GSE36640 | Up | 0.6744508567 |
| GSE54402 | Up | 0.4149648210 |
| GSE9593 | Down | -0.0353424860 |
| GSE43922 | Up | 1.2047668109 |
| GSE24585 | Up | 0.0662427279 |
| GSE37065 | Up | 1.1181017296 |
| GSE28863_A1 | Down | -0.3933271258 |
| GSE28863_A2 | Down | -0.1691923327 |
| GSE28863_A3 | Up | 0.4397487507 |
| GSE28863_A4 | Up | 0.0702041745 |
| GSE48662 | Up | 0.3107370192 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018818 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030133 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
