HCSGD entry for NRG4
1. General information
| Official gene symbol | NRG4 |
|---|---|
| Entrez ID | 145957 |
| Gene full name | neuregulin 4 |
| Other gene symbols | HRG4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0008083 | Growth factor activity | IEA | molecular_function |
| GO:0008543 | Fibroblast growth factor receptor signaling pathway | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0048015 | Phosphatidylinositol-mediated signaling | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2810710307 | 0.8891537404 | 0.9785288416 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2180799966 |
| GSE13712_SHEAR | Down | -0.3131724957 |
| GSE13712_STATIC | Down | -0.1188413245 |
| GSE19018 | Up | 0.0496616059 |
| GSE19899_A1 | Up | 0.0586158307 |
| GSE19899_A2 | Down | -0.0411661783 |
| PubMed_21979375_A1 | Up | 0.2208555793 |
| PubMed_21979375_A2 | Up | 0.1037702853 |
| GSE35957 | Up | 0.2392644470 |
| GSE36640 | Down | -0.0074692155 |
| GSE54402 | Up | 0.0730736801 |
| GSE9593 | Up | 0.0272384055 |
| GSE43922 | Up | 0.0220944726 |
| GSE24585 | Up | 0.7044619651 |
| GSE37065 | Up | 0.0397747301 |
| GSE28863_A1 | Down | -0.0092202642 |
| GSE28863_A2 | Down | -0.0714768625 |
| GSE28863_A3 | Up | 0.0045127529 |
| GSE28863_A4 | Down | -0.1010947055 |
| GSE48662 | Up | 0.4777714686 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024936 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026870 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
