HCSGD entry for CSHL1
1. General information
| Official gene symbol | CSHL1 |
|---|---|
| Entrez ID | 1444 |
| Gene full name | chorionic somatomammotropin hormone-like 1 |
| Other gene symbols | CS-5 CSHP1 CSL hCS-L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005179 | Hormone activity | IEA NAS | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7557735914 | 0.8674446032 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1142017380 |
| GSE13712_SHEAR | Down | -0.0967556404 |
| GSE13712_STATIC | Down | -0.0891750879 |
| GSE19018 | Up | 0.0615538240 |
| GSE19899_A1 | Up | 0.0091757420 |
| GSE19899_A2 | Up | 0.0476262355 |
| PubMed_21979375_A1 | Down | -0.0152477055 |
| PubMed_21979375_A2 | Down | -0.0588663758 |
| GSE35957 | Down | -0.0136166719 |
| GSE36640 | Up | 0.0571295096 |
| GSE54402 | Down | -0.0031355745 |
| GSE9593 | Up | 0.0891067804 |
| GSE43922 | Up | 0.1532966145 |
| GSE24585 | Up | 0.0925818968 |
| GSE37065 | Down | -0.0718102270 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0021154039 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT002476 | proteomics analysis | Functional MTI (Weak) | 18362358 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | {phenotypic analysis of target gene} | {overexpression} | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 24931169 | Notch-induced senescence involves canonical CSL/RBPJ-dependent transcriptional activity and the p16(INK4A)-Rb pathway |
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