HCSGD entry for CRYM

1. General information

Official gene symbolCRYM
Entrez ID1428
Gene full namecrystallin, mu
Other gene symbolsDFNA40 THBP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIMPbiological_process
GO:0003714Transcription corepressor activityIMPmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0007605Sensory perception of soundIMPbiological_process
GO:0042403Thyroid hormone metabolic processIEAbiological_process
GO:0042562Hormone bindingIEAmolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0047127Thiomorpholine-carboxylate dehydrogenase activityIEAmolecular_function
GO:0050661NADP bindingIDAmolecular_function
GO:0070324Thyroid hormone bindingIDA IMPmolecular_function
GO:0070327Thyroid hormone transportIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03148794120.97837419550.41029410891.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0092119500
GSE13712_SHEARUp0.0053042937
GSE13712_STATICDown-0.0861847488
GSE19018Up0.1963766319
GSE19899_A1Down-0.0988869915
GSE19899_A2Up0.4670058602
PubMed_21979375_A1Up0.3777065001
PubMed_21979375_A2Up0.3727828920
GSE35957Up0.2521087655
GSE36640Up0.5305121422
GSE54402Up0.6775597611
GSE9593Up0.1494174466
GSE43922Up0.0447027578
GSE24585Up1.5097319176
GSE37065Up0.1252361524
GSE28863_A1Down-0.0870265320
GSE28863_A2Up0.0511059105
GSE28863_A3Up0.3292988944
GSE28863_A4Up0.0218627725
GSE48662Down-0.1415588600

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NRP409DB05235 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.