HCSGD entry for DUSP19

1. General information

Official gene symbolDUSP19
Entrez ID142679
Gene full namedual specificity phosphatase 19
Other gene symbolsDUSP17 LMWDSP3 SKRP1 TS-DSP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000188Inactivation of MAPK activityIEAbiological_process
GO:0004725Protein tyrosine phosphatase activityIEAmolecular_function
GO:0004860Protein kinase inhibitor activityISSmolecular_function
GO:0005078MAP-kinase scaffold activityISSmolecular_function
GO:0005737CytoplasmIBAcellular_component
GO:0006469Negative regulation of protein kinase activityISSbiological_process
GO:0006470Protein dephosphorylationIBAbiological_process
GO:0007254JNK cascadeIBAbiological_process
GO:0008330Protein tyrosine/threonine phosphatase activityIEAmolecular_function
GO:0008579JUN kinase phosphatase activityIBAmolecular_function
GO:0030295Protein kinase activator activityISSmolecular_function
GO:0031435Mitogen-activated protein kinase kinase kinase bindingISSmolecular_function
GO:0043410Positive regulation of MAPK cascadeISSbiological_process
GO:0043507Positive regulation of JUN kinase activityISSbiological_process
GO:0043508Negative regulation of JUN kinase activityISSbiological_process
GO:0045860Positive regulation of protein kinase activityISSbiological_process
GO:0046329Negative regulation of JNK cascadeISSbiological_process
GO:0046330Positive regulation of JNK cascadeISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91065030200.04145163940.99999024730.3832915028

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1038202666
GSE13712_SHEARDown-0.0331796316
GSE13712_STATICUp0.2244742638
GSE19018Down-0.2463387774
GSE19899_A1Down-0.1344480228
GSE19899_A2Down-0.3993305081
PubMed_21979375_A1Down-0.3373428564
PubMed_21979375_A2Down-0.3417733319
GSE35957Down-0.0918188629
GSE36640Down-0.0563332651
GSE54402Down-0.0638395581
GSE9593Down-0.0267162573
GSE43922Down-0.0802746607
GSE24585Up1.0284549090
GSE37065Down-0.0091832240
GSE28863_A1Down-0.4110842821
GSE28863_A2Down-0.4685402119
GSE28863_A3Down-0.9146069375
GSE28863_A4Down-0.1465674701
GSE48662Up0.1280942498

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.