HCSGD entry for UBE2F


1. General information

Official gene symbolUBE2F
Entrez ID140739
Gene full nameubiquitin-conjugating enzyme E2F (putative)
Other gene symbolsNCE2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0016881Acid-amino acid ligase activityIEAmolecular_function
GO:0019788NEDD8 ligase activityIDAmolecular_function
GO:0045116Protein neddylationIDA IEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08187407770.92529916420.60341564951.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1835083240
GSE13712_SHEARUp0.0827311017
GSE13712_STATICDown-0.0825285595
GSE19018Down-0.5315938129
GSE19899_A1Down-0.0334726019
GSE19899_A2Up0.7401473512
PubMed_21979375_A1Up0.6544889092
PubMed_21979375_A2Up0.1906757226
GSE35957Up0.7106564877
GSE36640Up0.5402630282
GSE54402Up0.1930106025
GSE9593Up0.3517827782
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.1327948695
GSE28863_A2Up0.1937851150
GSE28863_A3Down-0.3888361490
GSE28863_A4Down-0.0615592182
GSE48662Down-0.0395840448

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT004083Luciferase reporter assayNon-Functional MTI18185580
hsa-miR-129-5pMIMAT0000242MIRT006660Luciferase reporter assayNon-Functional MTI19887623
hsa-miR-129-2-3pMIMAT0004605MIRT006661Luciferase reporter assayNon-Functional MTI19887623
hsa-miR-615-3pMIMAT0003283MIRT040036CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.