HCSGD entry for DYNLL2
1. General information
| Official gene symbol | DYNLL2 |
|---|---|
| Entrez ID | 140735 |
| Gene full name | dynein, light chain, LC8-type 2 |
| Other gene symbols | DNCL1B Dlc2 RSPH22 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003774 | Motor activity | IEA | molecular_function |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0007017 | Microtubule-based process | IEA | biological_process |
| GO:0008039 | Synaptic target recognition | IEA | biological_process |
| GO:0008092 | Cytoskeletal protein binding | IEA | molecular_function |
| GO:0016459 | Myosin complex | ISS | cellular_component |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0030286 | Dynein complex | IEA | cellular_component |
| GO:0097193 | Intrinsic apoptotic signaling pathway | TAS | biological_process |
| GO:1900740 | Positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1972407241 | 0.3034097337 | 0.8590836367 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4793834121 |
| GSE13712_SHEAR | Up | 0.6749360923 |
| GSE13712_STATIC | Up | 0.3723870024 |
| GSE19018 | Down | -0.3264857234 |
| GSE19899_A1 | Down | -0.4747365121 |
| GSE19899_A2 | Down | -0.3378879771 |
| PubMed_21979375_A1 | Down | -0.4622534216 |
| PubMed_21979375_A2 | Down | -0.3582908594 |
| GSE35957 | Up | 0.2318957208 |
| GSE36640 | Down | -0.0377521940 |
| GSE54402 | Up | 0.1406176125 |
| GSE9593 | Up | 0.4043630410 |
| GSE43922 | Down | -0.3473436851 |
| GSE24585 | Up | 0.2709012507 |
| GSE37065 | Up | 0.1201047021 |
| GSE28863_A1 | Up | 0.2153264964 |
| GSE28863_A2 | Up | 0.5432922403 |
| GSE28863_A3 | Down | -0.2713332264 |
| GSE28863_A4 | Down | -0.1943707007 |
| GSE48662 | Down | -0.1625428344 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020140 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT025997 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031095 | Sequencing | Functional MTI (Weak) | 20371350 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
