HCSGD entry for TRIM69
1. General information
| Official gene symbol | TRIM69 |
|---|---|
| Entrez ID | 140691 |
| Gene full name | tripartite motif containing 69 |
| Other gene symbols | HSD34 RNF36 Trif |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4788202766 | 0.1728017553 | 0.9999902473 | 0.8047253317 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0576316606 |
| GSE13712_SHEAR | Up | 0.5094725668 |
| GSE13712_STATIC | Up | 0.4657931949 |
| GSE19018 | Down | -0.0414450378 |
| GSE19899_A1 | Down | -0.2004573797 |
| GSE19899_A2 | Down | -0.6388682249 |
| PubMed_21979375_A1 | Down | -0.5075911634 |
| PubMed_21979375_A2 | Down | -0.3657513500 |
| GSE35957 | Down | -0.6320880552 |
| GSE36640 | Down | -0.0778865104 |
| GSE54402 | Down | -0.5959287227 |
| GSE9593 | Down | -0.0697364804 |
| GSE43922 | Up | 0.0079916867 |
| GSE24585 | Up | 0.0136969504 |
| GSE37065 | Up | 0.5713468620 |
| GSE28863_A1 | Down | -0.1307964691 |
| GSE28863_A2 | Up | 0.5861359207 |
| GSE28863_A3 | Down | -0.1653395293 |
| GSE28863_A4 | Up | 0.0548317189 |
| GSE48662 | Up | 0.4492097394 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018647 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
