HCSGD entry for HAPLN1
1. General information
| Official gene symbol | HAPLN1 |
|---|---|
| Entrez ID | 1404 |
| Gene full name | hyaluronan and proteoglycan link protein 1 |
| Other gene symbols | CRTL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005540 | Hyaluronic acid binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0031012 | Extracellular matrix | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0724764637 | 0.0648003153 | 0.5732130409 | 0.4805886447 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0801249528 |
| GSE13712_SHEAR | Down | -0.0341356532 |
| GSE13712_STATIC | Up | 0.0136100252 |
| GSE19018 | Up | 0.0146226377 |
| GSE19899_A1 | Up | 0.0406823493 |
| GSE19899_A2 | Up | 0.1384379721 |
| PubMed_21979375_A1 | Down | -0.0466684704 |
| PubMed_21979375_A2 | Down | -0.0966026074 |
| GSE35957 | Up | 0.2181350351 |
| GSE36640 | Up | 4.3888378459 |
| GSE54402 | Down | -0.0263483823 |
| GSE9593 | Up | 0.0121698615 |
| GSE43922 | Up | 0.0162487853 |
| GSE24585 | Down | -0.2399985178 |
| GSE37065 | Down | -0.2895798903 |
| GSE28863_A1 | Down | -0.8091772167 |
| GSE28863_A2 | Down | -0.4713789989 |
| GSE28863_A3 | Down | -0.3197171598 |
| GSE28863_A4 | Up | 0.6239640187 |
| GSE48662 | Down | -0.5946875196 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Hyaluronic acid | DB08818 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017946 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030924 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
