HCSGD entry for ADORA3

1. General information

Official gene symbolADORA3
Entrez ID140
Gene full nameadenosine A3 receptor
Other gene symbolsA3AR AD026 bA552M11.5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001609G-protein coupled adenosine receptor activityIEAmolecular_function
GO:0002553Histamine secretion by mast cellIEAbiological_process
GO:0002687Positive regulation of leukocyte migrationIEAbiological_process
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006954Inflammatory responseTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007190Activation of adenylate cyclase activityTASbiological_process
GO:0008016Regulation of heart contractionTASbiological_process
GO:0009611Response to woundingTASbiological_process
GO:0014068Positive regulation of phosphatidylinositol 3-kinase signalingIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0042629Mast cell granuleIEAcellular_component
GO:0043306Positive regulation of mast cell degranulationIEAbiological_process
GO:0050729Positive regulation of inflammatory responseIEAbiological_process
GO:0050850Positive regulation of calcium-mediated signalingIEAbiological_process
GO:0070257Positive regulation of mucus secretionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.79774628240.87386108050.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0513346460
GSE13712_SHEARDown-0.1589941202
GSE13712_STATICDown-0.0127558597
GSE19018Down-0.0496724310
GSE19899_A1Up0.0288559365
GSE19899_A2Up0.0337426908
PubMed_21979375_A1Up0.0896628279
PubMed_21979375_A2Up0.0261261151
GSE35957Up0.0133040974
GSE36640Up0.0235047172
GSE54402Up0.0146055714
GSE9593Down-0.2044971328
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.0472406672
GSE28863_A2Up0.1595667342
GSE28863_A3Up0.1699874243
GSE28863_A4Up0.1513741304
GSE48662Down-0.0565418723

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

EnprofyllineDB00824 APRD00273
AminophyllineDB01223 APRD00329
CF-101DB05511 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.