HCSGD entry for CRHR1

1. General information

Official gene symbolCRHR1
Entrez ID1394
Gene full namecorticotropin releasing hormone receptor 1
Other gene symbolsCRF-R CRF-R-1 CRF-R1 CRF1 CRFR-1 CRFR1 CRH-R-1 CRH-R1 CRH-R1h CRHR CRHR1L CRHR1f
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIEAbiological_process
GO:0001965G-protein alpha-subunit bindingIEAmolecular_function
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005771Multivesicular bodyIEAcellular_component
GO:0005802Trans-Golgi networkIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006955Immune responseTASbiological_process
GO:0007190Activation of adenylate cyclase activityTASbiological_process
GO:0007200Phospholipase C-activating G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIEAbiological_process
GO:0007218Neuropeptide signaling pathwayIEAbiological_process
GO:0007565Female pregnancyNASbiological_process
GO:0007567ParturitionTASbiological_process
GO:0007613MemoryIEAbiological_process
GO:0008542Visual learningIEAbiological_process
GO:0010578Regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathwayIMPbiological_process
GO:0010579Positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathwayIDAbiological_process
GO:0015056Corticotrophin-releasing factor receptor activityIDAmolecular_function
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIDA IEAcellular_component
GO:0021854Hypothalamus developmentIEAbiological_process
GO:0030325Adrenal gland developmentIEAbiological_process
GO:0030425DendriteIEAcellular_component
GO:0030855Epithelial cell differentiationIEAbiological_process
GO:0031226Intrinsic component of plasma membraneIDAcellular_component
GO:0031982VesicleIEAcellular_component
GO:0032403Protein complex bindingIEAmolecular_function
GO:0032811Negative regulation of epinephrine secretionIEAbiological_process
GO:0035641Locomotory exploration behaviorIEAbiological_process
GO:0035902Response to immobilization stressIEAbiological_process
GO:0042596Fear responseIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043306Positive regulation of mast cell degranulationIEAbiological_process
GO:0043404Corticotropin-releasing hormone receptor activityIEAmolecular_function
GO:0045177Apical part of cellIEAcellular_component
GO:0048148Behavioral response to cocaineIEAbiological_process
GO:0048149Behavioral response to ethanolIEAbiological_process
GO:0048266Behavioral response to painIEAbiological_process
GO:0051424Corticotropin-releasing hormone bindingIEAmolecular_function
GO:0051458Corticotropin secretionISSbiological_process
GO:0051867General adaptation syndrome, behavioral processIEAbiological_process
GO:0060291Long-term synaptic potentiationIEAbiological_process
GO:0071376Cellular response to corticotropin-releasing hormone stimulusIDAbiological_process
GO:1901215Negative regulation of neuron deathIEAbiological_process
GO:1901386Negative regulation of voltage-gated calcium channel activityIDAbiological_process
GO:2000252Negative regulation of feeding behaviorIEAbiological_process
GO:2000852Regulation of corticosterone secretionISSbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80771913680.83002449000.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0227627776
GSE13712_SHEARDown-0.1843223254
GSE13712_STATICDown-0.1155640509
GSE19018Up0.0844066627
GSE19899_A1Down-0.0213541855
GSE19899_A2Down-0.0638349896
PubMed_21979375_A1Up0.0592332184
PubMed_21979375_A2Down-0.1415499267
GSE35957Up0.0180356940
GSE36640Up0.0229755640
GSE54402Down-0.0894761865
GSE9593Down-0.0292142996
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.0540076153
GSE28863_A2Up0.0586844946
GSE28863_A3Up0.3829705492
GSE28863_A4Up0.1173206226
GSE48662Up0.1025890865

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.