HCSGD entry for CRHBP

1. General information

Official gene symbolCRHBP
Entrez ID1393
Gene full namecorticotropin releasing hormone binding protein
Other gene symbolsCRF-BP CRFBP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001963Synaptic transmission, dopaminergicISSbiological_process
GO:0002125Maternal aggressive behaviorISSbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0005622IntracellularISScellular_component
GO:0005634NucleusISScellular_component
GO:0005767Secondary lysosomeISScellular_component
GO:0005771Multivesicular bodyISScellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0005874MicrotubuleISScellular_component
GO:0006954Inflammatory responseIDAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007565Female pregnancyIDA IEPbiological_process
GO:0007610BehaviorISSbiological_process
GO:0007611Learning or memoryTASbiological_process
GO:0009755Hormone-mediated signaling pathwayIDAbiological_process
GO:0030141Secretory granuleIDAcellular_component
GO:0030425DendriteISScellular_component
GO:0031045Dense core granuleISScellular_component
GO:0033554Cellular response to stressIMPbiological_process
GO:0035690Cellular response to drugISSbiological_process
GO:0035865Cellular response to potassium ionIDAbiological_process
GO:0042277Peptide bindingISSmolecular_function
GO:0042445Hormone metabolic processIEAbiological_process
GO:0043196VaricosityISScellular_component
GO:0043204PerikaryonISScellular_component
GO:0043679Axon terminusISScellular_component
GO:0045055Regulated secretory pathwayIDAbiological_process
GO:0048149Behavioral response to ethanolIMPbiological_process
GO:0050795Regulation of behaviorIMPbiological_process
GO:0051424Corticotropin-releasing hormone bindingIDA IPImolecular_function
GO:0051459Regulation of corticotropin secretionIDAbiological_process
GO:0051460Negative regulation of corticotropin secretionIDAbiological_process
GO:0071277Cellular response to calcium ionISSbiological_process
GO:0071314Cellular response to cocaineISSbiological_process
GO:0071320Cellular response to cAMPISSbiological_process
GO:0071356Cellular response to tumor necrosis factorIDAbiological_process
GO:0071391Cellular response to estrogen stimulusIDAbiological_process
GO:0071392Cellular response to estradiol stimulusIDAbiological_process
GO:0097211Cellular response to gonadotropin-releasing hormoneISSbiological_process
GO:1900011Negative regulation of corticotropin-releasing hormone receptor activityIDAbiological_process
GO:2000310Regulation of N-methyl-D-aspartate selective glutamate receptor activityISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31499948330.74476634630.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1379070397
GSE13712_SHEARDown-0.0225866868
GSE13712_STATICDown-0.3862510775
GSE19018Down-0.1736841148
GSE19899_A1Up0.0680139598
GSE19899_A2Down-0.1825297143
PubMed_21979375_A1Up0.0455587778
PubMed_21979375_A2Down-0.0500009201
GSE35957Up0.1360647967
GSE36640Down-0.1339712528
GSE54402Up0.0136949258
GSE9593Up0.2225704420
GSE43922Down-0.1017361651
GSE24585Up0.3635856924
GSE37065Up1.1826960827
GSE28863_A1Down-0.0534261365
GSE28863_A2Up0.0141227283
GSE28863_A3Up0.1355620845
GSE28863_A4Up0.0972696399
GSE48662Up0.0029738062

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT002477proteomics analysisFunctional MTI (Weak)18362358
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    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-16-5pMIMAT0000069NAhsa-miR-16{phenotypic analysis of target gene}{overexpression}18362358
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.