HCSGD entry for NKX2-6

1. General information

Official gene symbolNKX2-6
Entrez ID137814
Gene full nameNK2 homeobox 6
Other gene symbolsCSX2 NKX2F NKX4-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIDA IEAmolecular_function
GO:0005634NucleusIC IEAcellular_component
GO:0006351Transcription, DNA-templatedIDAbiological_process
GO:0008284Positive regulation of cell proliferationIEA ISSbiological_process
GO:0021854Hypothalamus developmentIEA ISSbiological_process
GO:0030154Cell differentiationISSbiological_process
GO:0035050Embryonic heart tube developmentIEA IMP ISSbiological_process
GO:0043066Negative regulation of apoptotic processIEA ISSbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0043586Tongue developmentIEA ISSbiological_process
GO:0048565Digestive tract developmentIEA ISSbiological_process
GO:0055014Atrial cardiac muscle cell developmentIEA ISSbiological_process
GO:0055015Ventricular cardiac muscle cell developmentIEA ISSbiological_process
GO:0060037Pharyngeal system developmentIEA ISSbiological_process
GO:0060039Pericardium developmentIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94473983130.70928274380.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.1840253357
GSE24585Down-0.1590978562
GSE37065Down-0.0427937680
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0453115382

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.