HCSGD entry for CPT2


1. General information

Official gene symbolCPT2
Entrez ID1376
Gene full namecarnitine palmitoyltransferase 2
Other gene symbolsCPT1 CPTASE IIAE4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004095Carnitine O-palmitoyltransferase activityNASmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005743Mitochondrial inner membraneNAS TAScellular_component
GO:0006635Fatty acid beta-oxidationIEAbiological_process
GO:0006853Carnitine shuttleTASbiological_process
GO:0044255Cellular lipid metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34565929870.47025702670.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2708120286
GSE13712_SHEARDown-0.0106730739
GSE13712_STATICUp0.0904360761
GSE19018Down-0.0549029277
GSE19899_A1Up0.1383271771
GSE19899_A2Up0.4902708225
PubMed_21979375_A1Down-0.4865591122
PubMed_21979375_A2Up0.1351556176
GSE35957Down-0.0894742991
GSE36640Up0.0426238585
GSE54402Up0.2242971457
GSE9593Down-0.4208628039
GSE43922Up0.1254494060
GSE24585Up0.4835212603
GSE37065Down-0.0742220460
GSE28863_A1Up0.0099612043
GSE28863_A2Up0.0976951708
GSE28863_A3Down-0.6282120078
GSE28863_A4Down-0.3096910341
GSE48662Down-0.0437718644

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-CarnitineDB00583 APRD01070
PerhexilineDB01074 APRD00107

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT025385ProteomicsFunctional MTI (Weak)21566225
hsa-miR-378a-3pMIMAT0000732MIRT043910CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.