HCSGD entry for CPT1A
1. General information
| Official gene symbol | CPT1A |
|---|---|
| Entrez ID | 1374 |
| Gene full name | carnitine palmitoyltransferase 1A (liver) |
| Other gene symbols | CPT1 CPT1-L L-CPT1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001676 | Long-chain fatty acid metabolic process | IDA IEA | biological_process |
| GO:0004095 | Carnitine O-palmitoyltransferase activity | IDA IEA | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | TAS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0006006 | Glucose metabolic process | IEA | biological_process |
| GO:0006635 | Fatty acid beta-oxidation | IEA | biological_process |
| GO:0006641 | Triglyceride metabolic process | IEA | biological_process |
| GO:0006853 | Carnitine shuttle | TAS | biological_process |
| GO:0009437 | Carnitine metabolic process | IDA | biological_process |
| GO:0014070 | Response to organic cyclic compound | IEA | biological_process |
| GO:0016746 | Transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0031307 | Integral component of mitochondrial outer membrane | IEA ISS | cellular_component |
| GO:0032000 | Positive regulation of fatty acid beta-oxidation | IEA | biological_process |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0042755 | Eating behavior | IEA | biological_process |
| GO:0042802 | Identical protein binding | IEA | molecular_function |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050796 | Regulation of insulin secretion | IEA | biological_process |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
| GO:0071398 | Cellular response to fatty acid | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0315963109 | 0.9659345048 | 0.4109113636 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0604324449 |
| GSE13712_SHEAR | Down | -0.0951958678 |
| GSE13712_STATIC | Up | 0.1353404641 |
| GSE19018 | Down | -0.2666305894 |
| GSE19899_A1 | Up | 0.0355845008 |
| GSE19899_A2 | Up | 0.4219718835 |
| PubMed_21979375_A1 | Up | 0.3530318042 |
| PubMed_21979375_A2 | Up | 0.6473829984 |
| GSE35957 | Down | -0.3931599402 |
| GSE36640 | Up | 0.6234253161 |
| GSE54402 | Up | 0.0008275952 |
| GSE9593 | Up | 0.1714539422 |
| GSE43922 | Up | 0.1914718830 |
| GSE24585 | Up | 0.7356096400 |
| GSE37065 | Up | 0.2807955352 |
| GSE28863_A1 | Up | 0.3994311587 |
| GSE28863_A2 | Up | 0.4764275562 |
| GSE28863_A3 | Down | -0.2405706389 |
| GSE28863_A4 | Up | 0.1967616432 |
| GSE48662 | Up | 0.2221093463 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-370-3p | MIMAT0000722 | MIRT004535 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 20124555 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020838 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031747 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048093 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
