HCSGD entry for CPOX
1. General information
| Official gene symbol | CPOX |
|---|---|
| Entrez ID | 1371 |
| Gene full name | coproporphyrinogen oxidase |
| Other gene symbols | CPO CPX HCP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004109 | Coproporphyrinogen oxidase activity | IEA TAS | molecular_function |
| GO:0005212 | Structural constituent of eye lens | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005758 | Mitochondrial intermembrane space | TAS | cellular_component |
| GO:0006778 | Porphyrin-containing compound metabolic process | TAS | biological_process |
| GO:0006779 | Porphyrin-containing compound biosynthetic process | IEA | biological_process |
| GO:0006782 | Protoporphyrinogen IX biosynthetic process | IEA | biological_process |
| GO:0006783 | Heme biosynthetic process | TAS | biological_process |
| GO:0010039 | Response to iron ion | IEA | biological_process |
| GO:0010288 | Response to lead ion | IEA | biological_process |
| GO:0017085 | Response to insecticide | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046685 | Response to arsenic-containing substance | IEA | biological_process |
| GO:0051597 | Response to methylmercury | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5293675848 | 0.2366457353 | 0.9999902473 | 0.9365289731 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2662248591 |
| GSE13712_SHEAR | Down | -0.0845107208 |
| GSE13712_STATIC | Down | -0.0927835823 |
| GSE19018 | Up | 0.5409201518 |
| GSE19899_A1 | Up | 0.4090893426 |
| GSE19899_A2 | Down | -0.0442067566 |
| PubMed_21979375_A1 | Up | 0.3197756737 |
| PubMed_21979375_A2 | Up | 0.0054371568 |
| GSE35957 | Down | -0.1399049049 |
| GSE36640 | Down | -0.6243363728 |
| GSE54402 | Up | 0.0392854741 |
| GSE9593 | Down | -0.0035621298 |
| GSE43922 | Up | 0.2035535963 |
| GSE24585 | Down | -0.3338401287 |
| GSE37065 | Down | -0.0462027031 |
| GSE28863_A1 | Down | -0.0794090490 |
| GSE28863_A2 | Up | 0.2462407619 |
| GSE28863_A3 | Down | -0.2040375411 |
| GSE28863_A4 | Down | -0.2376688356 |
| GSE48662 | Down | -0.1185166968 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001374 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-375 | MIMAT0000728 | MIRT019712 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT020103 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022424 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027462 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028461 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-937-3p | MIMAT0004980 | MIRT036635 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046519 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047853 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
