HCSGD entry for CLDN23
1. General information
| Official gene symbol | CLDN23 |
|---|---|
| Entrez ID | 137075 |
| Gene full name | claudin 23 |
| Other gene symbols | CLDNL hCG1646163 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005923 | Tight junction | ISS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016338 | Calcium-independent cell-cell adhesion | ISS | biological_process |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0042802 | Identical protein binding | ISS | molecular_function |
| GO:0045216 | Cell-cell junction organization | TAS | biological_process |
| GO:0070830 | Tight junction assembly | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8851125223 | 0.0377465408 | 0.9999902473 | 0.3663446534 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0329751806 |
| GSE13712_SHEAR | Up | 0.1017602451 |
| GSE13712_STATIC | Up | 0.0915037248 |
| GSE19018 | Down | -0.4925301447 |
| GSE19899_A1 | Down | -0.2826021614 |
| GSE19899_A2 | Down | -1.4719850775 |
| PubMed_21979375_A1 | Down | -0.6317838607 |
| PubMed_21979375_A2 | Down | -0.0270210858 |
| GSE35957 | Down | -0.6114782151 |
| GSE36640 | Down | -1.3559779139 |
| GSE54402 | Down | -0.4251022938 |
| GSE9593 | Up | 0.2888748097 |
| GSE43922 | Down | -0.0003157619 |
| GSE24585 | Up | 0.1277152042 |
| GSE37065 | Up | 0.1481390277 |
| GSE28863_A1 | Down | -0.0375799332 |
| GSE28863_A2 | Up | 0.0993014641 |
| GSE28863_A3 | Up | 0.1532154427 |
| GSE28863_A4 | Up | 0.0689421001 |
| GSE48662 | Down | -0.1072689300 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT045021 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046704 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
