HCSGD entry for CPB2

1. General information

Official gene symbolCPB2
Entrez ID1361
Gene full namecarboxypeptidase B2 (plasma)
Other gene symbolsCPU PCPB TAFI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003331Positive regulation of extracellular matrix constituent secretionIEAbiological_process
GO:0004181Metallocarboxypeptidase activityIEAmolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0007596Blood coagulationIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009408Response to heatIEAbiological_process
GO:0010757Negative regulation of plasminogen activationIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042730FibrinolysisIEAbiological_process
GO:0051918Negative regulation of fibrinolysisIEAbiological_process
GO:0071333Cellular response to glucose stimulusIEAbiological_process
GO:0097421Liver regenerationIEAbiological_process
GO:2000346Negative regulation of hepatocyte proliferationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.89519205200.64393222140.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1355406767
GSE13712_SHEARDown-0.0489592982
GSE13712_STATICUp0.0365986251
GSE19018Down-0.0188467963
GSE19899_A1Down-0.0761779990
GSE19899_A2Up0.0745883149
PubMed_21979375_A1Down-0.0486649658
PubMed_21979375_A2Down-0.0518662830
GSE35957Up0.0675354491
GSE36640Down-0.2274015981
GSE54402Up0.1335480485
GSE9593Down-0.1615957252
GSE43922Up0.0137196001
GSE24585Down-0.1378639026
GSE37065Down-0.0408684488
GSE28863_A1Up0.0430227359
GSE28863_A2Down-0.0469332720
GSE28863_A3Down-0.0099212064
GSE28863_A4Up0.0329410193
GSE48662Up0.0358330881

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

AZD-9684DB05712 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029527MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.