HCSGD entry for CPA3
1. General information
| Official gene symbol | CPA3 |
|---|---|
| Entrez ID | 1359 |
| Gene full name | carboxypeptidase A3 (mast cell) |
| Other gene symbols | MC-CPA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002003 | Angiotensin maturation | TAS | biological_process |
| GO:0004181 | Metallocarboxypeptidase activity | NAS TAS | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0006508 | Proteolysis | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0030133 | Transport vesicle | IEA | cellular_component |
| GO:0030141 | Secretory granule | NAS | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0160998062 | 0.6866194218 | 0.3127402214 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1525505228 |
| GSE13712_SHEAR | Down | -0.1562485589 |
| GSE13712_STATIC | Down | -2.7538651787 |
| GSE19018 | Down | -0.0180935371 |
| GSE19899_A1 | Up | 0.5400037543 |
| GSE19899_A2 | Up | 1.4896203295 |
| PubMed_21979375_A1 | Up | 1.6565045100 |
| PubMed_21979375_A2 | Up | 3.6737482148 |
| GSE35957 | Down | -0.6190001509 |
| GSE36640 | Down | -0.1425876218 |
| GSE54402 | Down | -0.0275691390 |
| GSE9593 | Up | 0.4499224995 |
| GSE43922 | Up | 0.3576630919 |
| GSE24585 | Up | 0.0935983607 |
| GSE37065 | Down | -0.0240512646 |
| GSE28863_A1 | Up | 0.0845598887 |
| GSE28863_A2 | Up | 0.5933052569 |
| GSE28863_A3 | Up | 0.1569092838 |
| GSE28863_A4 | Down | -0.0716720714 |
| GSE48662 | Down | -0.1371534882 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019464 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT023344 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
