HCSGD entry for STXBP5
1. General information
| Official gene symbol | STXBP5 |
|---|---|
| Entrez ID | 134957 |
| Gene full name | syntaxin binding protein 5 (tomosyn) |
| Other gene symbols | LGL3 LLGL3 Nbla04300 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005892 | Acetylcholine-gated channel complex | ISS | cellular_component |
| GO:0006887 | Exocytosis | IEA | biological_process |
| GO:0008021 | Synaptic vesicle | IEA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0017075 | Syntaxin-1 binding | ISS | molecular_function |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030659 | Cytoplasmic vesicle membrane | IEA | cellular_component |
| GO:0045921 | Positive regulation of exocytosis | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5137376467 | 0.0267509897 | 0.9999902473 | 0.3132174377 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4776260349 |
| GSE13712_SHEAR | Up | 0.5241970797 |
| GSE13712_STATIC | Up | 0.2601169739 |
| GSE19018 | Down | -0.3528712179 |
| GSE19899_A1 | Down | -0.0391927899 |
| GSE19899_A2 | Down | -0.7756876498 |
| PubMed_21979375_A1 | Down | -0.5311547991 |
| PubMed_21979375_A2 | Down | -0.7052786635 |
| GSE35957 | Up | 0.3495747483 |
| GSE36640 | Up | 0.2328557191 |
| GSE54402 | Down | -0.1018368534 |
| GSE9593 | Down | -0.5784396785 |
| GSE43922 | Down | -0.1123251664 |
| GSE24585 | Down | -0.6641317707 |
| GSE37065 | Down | -0.1148573747 |
| GSE28863_A1 | Up | 0.8374026219 |
| GSE28863_A2 | Up | 0.7912013779 |
| GSE28863_A3 | Down | -0.4540136614 |
| GSE28863_A4 | Down | -0.2240076353 |
| GSE48662 | Down | -0.0270158020 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030955 | Microarray | Functional MTI (Weak) | 20048743 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
