HCSGD entry for GRPEL2
1. General information
| Official gene symbol | GRPEL2 |
|---|---|
| Entrez ID | 134266 |
| Gene full name | GrpE-like 2, mitochondrial (E. coli) |
| Other gene symbols | Mt-GrpE#2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000774 | Adenyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | IEA | cellular_component |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0006626 | Protein targeting to mitochondrion | TAS | biological_process |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0051082 | Unfolded protein binding | IEA | molecular_function |
| GO:0051087 | Chaperone binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3899769538 | 0.1266742487 | 0.9999902473 | 0.6850612081 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0655413698 |
| GSE13712_SHEAR | Up | 1.6695814182 |
| GSE13712_STATIC | Up | 0.2667507700 |
| GSE19018 | Down | -0.2217090848 |
| GSE19899_A1 | Up | 0.0753244785 |
| GSE19899_A2 | Down | -0.3077046194 |
| PubMed_21979375_A1 | Up | 0.2102519945 |
| PubMed_21979375_A2 | Down | -0.4315932653 |
| GSE35957 | Down | -0.0603161134 |
| GSE36640 | Down | -0.6450434432 |
| GSE54402 | Up | 0.2664493415 |
| GSE9593 | Up | 0.2800045374 |
| GSE43922 | Up | 0.2536135006 |
| GSE24585 | Down | -0.0827404603 |
| GSE37065 | Down | -0.1075457831 |
| GSE28863_A1 | Down | -0.3604917147 |
| GSE28863_A2 | Down | -0.4259490567 |
| GSE28863_A3 | Down | -0.3429354003 |
| GSE28863_A4 | Down | -0.1602793782 |
| GSE48662 | Down | -0.0474080406 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT001628 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT001628 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-375 | MIMAT0000728 | MIRT019797 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028481 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030946 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031759 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039644 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
