HCSGD entry for KLF6
1. General information
| Official gene symbol | KLF6 |
|---|---|
| Entrez ID | 1316 |
| Gene full name | Kruppel-like factor 6 |
| Other gene symbols | BCD1 CBA1 COPEB CPBP GBF PAC1 ST12 ZF9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | IEA | biological_process |
| GO:0030183 | B cell differentiation | NAS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7993664033 | 0.0424338931 | 0.9999902473 | 0.3877461538 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5341128280 |
| GSE13712_SHEAR | Up | 0.5298240999 |
| GSE13712_STATIC | Up | 0.1202947151 |
| GSE19018 | Down | -0.0640781870 |
| GSE19899_A1 | Down | -0.2515714363 |
| GSE19899_A2 | Down | -0.2488111785 |
| PubMed_21979375_A1 | Up | 0.6329752689 |
| PubMed_21979375_A2 | Down | -0.6827937104 |
| GSE35957 | Down | -0.4598649016 |
| GSE36640 | Down | -0.0066639936 |
| GSE54402 | Up | 0.1097356941 |
| GSE9593 | Up | 0.2142527851 |
| GSE43922 | Down | -0.0753003606 |
| GSE24585 | Down | -0.9289273691 |
| GSE37065 | Down | -0.1319603616 |
| GSE28863_A1 | Up | 0.0541896088 |
| GSE28863_A2 | Down | -0.0692347083 |
| GSE28863_A3 | Down | -0.5197759746 |
| GSE28863_A4 | Up | 0.2485192270 |
| GSE48662 | Down | -0.2470235562 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181a-5p | MIMAT0000256 | MIRT006939 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 22581522 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022229 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT043589 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
