HCSGD entry for COPA
1. General information
| Official gene symbol | COPA |
|---|---|
| Entrez ID | 1314 |
| Gene full name | coatomer protein complex, subunit alpha |
| Other gene symbols | HEP-COP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005179 | Hormone activity | IEA | molecular_function |
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0006890 | Retrograde vesicle-mediated transport, Golgi to ER | TAS | biological_process |
| GO:0030126 | COPI vesicle coat | IDA ISS | cellular_component |
| GO:0030157 | Pancreatic juice secretion | IDA | biological_process |
| GO:0048205 | COPI coating of Golgi vesicle | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3253982409 | 0.3832438623 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4488353755 |
| GSE13712_SHEAR | Up | 0.0056031792 |
| GSE13712_STATIC | Up | 0.1766698946 |
| GSE19018 | Up | 0.0101842936 |
| GSE19899_A1 | Down | -0.1031128949 |
| GSE19899_A2 | Down | -0.2162153303 |
| PubMed_21979375_A1 | Down | -0.5786809027 |
| PubMed_21979375_A2 | Down | -0.0336884956 |
| GSE35957 | Up | 0.0574607045 |
| GSE36640 | Up | 0.2901308938 |
| GSE54402 | Up | 0.1075393588 |
| GSE9593 | Up | 0.5343590373 |
| GSE43922 | Up | 0.0122245673 |
| GSE24585 | Up | 0.2924096989 |
| GSE37065 | Down | -0.2429919615 |
| GSE28863_A1 | Up | 0.0293880418 |
| GSE28863_A2 | Up | 0.3934279936 |
| GSE28863_A3 | Down | -0.7106026607 |
| GSE28863_A4 | Down | -0.2856770384 |
| GSE48662 | Down | -0.0409089232 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017123 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037463 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-421 | MIMAT0003339 | MIRT039417 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040641 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041376 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042473 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046345 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047710 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052740 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
