HCSGD entry for KCNH8
1. General information
| Official gene symbol | KCNH8 |
|---|---|
| Entrez ID | 131096 |
| Gene full name | potassium voltage-gated channel, subfamily H (eag-related), member 8 |
| Other gene symbols | ELK ELK1 Kv12.1 elk3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000155 | Phosphorelay sensor kinase activity | IEA | molecular_function |
| GO:0005249 | Voltage-gated potassium channel activity | IBA IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IBA | cellular_component |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0042391 | Regulation of membrane potential | IBA | biological_process |
| GO:0071805 | Potassium ion transmembrane transport | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5968538467 | 0.8112756962 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0486060371 |
| GSE13712_SHEAR | Down | -0.1385149264 |
| GSE13712_STATIC | Down | -0.2295541609 |
| GSE19018 | Up | 0.0837908707 |
| GSE19899_A1 | Up | 0.5616290754 |
| GSE19899_A2 | Up | 0.2885341886 |
| PubMed_21979375_A1 | Up | 0.1119626603 |
| PubMed_21979375_A2 | Down | -0.2640658777 |
| GSE35957 | Down | -0.0395902731 |
| GSE36640 | Down | -0.0266154696 |
| GSE54402 | Up | 0.0498014417 |
| GSE9593 | Down | -0.0162024454 |
| GSE43922 | Up | 0.0087191115 |
| GSE24585 | Up | 0.0644323022 |
| GSE37065 | Up | 0.0464353355 |
| GSE28863_A1 | Up | 0.0280660095 |
| GSE28863_A2 | Up | 0.0857130339 |
| GSE28863_A3 | Up | 0.0045097498 |
| GSE28863_A4 | Down | -0.0371704039 |
| GSE48662 | Up | 0.0639924988 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019154 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
