HCSGD entry for SGPP2
1. General information
| Official gene symbol | SGPP2 |
|---|---|
| Entrez ID | 130367 |
| Gene full name | sphingosine-1-phosphate phosphatase 2 |
| Other gene symbols | SPP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0006670 | Sphingosine metabolic process | IDA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016311 | Dephosphorylation | IDA | biological_process |
| GO:0030148 | Sphingolipid biosynthetic process | TAS | biological_process |
| GO:0042392 | Sphingosine-1-phosphate phosphatase activity | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8835307739 | 0.0879408457 | 0.9999902473 | 0.5625008505 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0690072065 |
| GSE13712_SHEAR | Down | -0.1833506679 |
| GSE13712_STATIC | Up | 0.1173358077 |
| GSE19018 | Up | 0.0253725784 |
| GSE19899_A1 | Up | 0.0131930526 |
| GSE19899_A2 | Up | 0.0815991742 |
| PubMed_21979375_A1 | Up | 0.2287748675 |
| PubMed_21979375_A2 | Up | 0.0432693771 |
| GSE35957 | Up | 0.1038503338 |
| GSE36640 | Down | -0.2305853112 |
| GSE54402 | Up | 0.1887681628 |
| GSE9593 | Up | 0.0386277743 |
| GSE43922 | Up | 0.0116656092 |
| GSE24585 | Down | -1.2478264951 |
| GSE37065 | Down | -0.0744517669 |
| GSE28863_A1 | Down | -0.6082623931 |
| GSE28863_A2 | Down | -0.6967560041 |
| GSE28863_A3 | Up | 0.2042211882 |
| GSE28863_A4 | Up | 0.0037807319 |
| GSE48662 | Up | 0.0672374467 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048643 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
