HCSGD entry for CMPK2

1. General information

Official gene symbolCMPK2
Entrez ID129607
Gene full namecytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
Other gene symbolsTMPK2 TYKi UMP-CMPK2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004127Cytidylate kinase activityIDAmolecular_function
GO:0004550Nucleoside diphosphate kinase activityIDAmolecular_function
GO:0004798Thymidylate kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0006165Nucleoside diphosphate phosphorylationIDAbiological_process
GO:0006227DUDP biosynthetic processIEAbiological_process
GO:0006233DTDP biosynthetic processIEAbiological_process
GO:0009142Nucleoside triphosphate biosynthetic processIDAbiological_process
GO:0033862UMP kinase activityIDAmolecular_function
GO:0071222Cellular response to lipopolysaccharideIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00010579010.86478523230.02812626261.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5677607249
GSE13712_SHEARUp7.3429259476
GSE13712_STATICUp3.7491641967
GSE19018Down-0.2558513859
GSE19899_A1Up0.0502816766
GSE19899_A2Up0.8691287319
PubMed_21979375_A1Up2.3453608968
PubMed_21979375_A2Up1.5582574353
GSE35957Down-4.5746177414
GSE36640Up1.9877720526
GSE54402Up2.9853372285
GSE9593Down-0.0858356898
GSE43922Up0.2214862803
GSE24585Up0.0471156098
GSE37065Up1.4708681619
GSE28863_A1Down-0.0556248309
GSE28863_A2Up0.8758877076
GSE28863_A3Up0.3031439441
GSE28863_A4Up0.0999024063
GSE48662Up0.0217448695

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-192-5pMIMAT0000222MIRT026932MicroarrayFunctional MTI (Weak)19074876
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.