HCSGD entry for COL6A1
1. General information
| Official gene symbol | COL6A1 |
|---|---|
| Entrez ID | 1291 |
| Gene full name | collagen, type VI, alpha 1 |
| Other gene symbols | OPLL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | IDA TAS | cellular_component |
| GO:0005589 | Collagen type VI | NAS | cellular_component |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0022617 | Extracellular matrix disassembly | TAS | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030574 | Collagen catabolic process | TAS | biological_process |
| GO:0031012 | Extracellular matrix | IDA ISS | cellular_component |
| GO:0042383 | Sarcolemma | IEA | cellular_component |
| GO:0043234 | Protein complex | IPI | cellular_component |
| GO:0048407 | Platelet-derived growth factor binding | IDA | molecular_function |
| GO:0070208 | Protein heterotrimerization | IPI | biological_process |
| GO:0071230 | Cellular response to amino acid stimulus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0939301014 | 0.0541585844 | 0.6424984927 | 0.4383847786 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1015799400 |
| GSE13712_SHEAR | Down | -1.5942858083 |
| GSE13712_STATIC | Down | -0.9538297258 |
| GSE19018 | Down | -0.1940409984 |
| GSE19899_A1 | Up | 0.0397032671 |
| GSE19899_A2 | Up | 0.1104824157 |
| PubMed_21979375_A1 | Up | 0.6830021507 |
| PubMed_21979375_A2 | Down | -0.0819029021 |
| GSE35957 | Down | -0.1927207988 |
| GSE36640 | Down | -0.8305101886 |
| GSE54402 | Down | -0.5821646697 |
| GSE9593 | Up | 0.6277287832 |
| GSE43922 | Down | -0.0055300413 |
| GSE24585 | Up | 0.2389230576 |
| GSE37065 | Down | -0.5468155250 |
| GSE28863_A1 | Up | 0.8842398953 |
| GSE28863_A2 | Up | 1.3428608192 |
| GSE28863_A3 | Up | 0.9121616679 |
| GSE28863_A4 | Down | -0.0117240775 |
| GSE48662 | Down | -0.1663176975 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018149 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-1301-3p | MIMAT0005797 | MIRT035972 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037192 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039896 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-5p | MIMAT0000761 | MIRT043222 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051548 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord

