HCSGD entry for COL6A1


1. General information

Official gene symbolCOL6A1
Entrez ID1291
Gene full namecollagen, type VI, alpha 1
Other gene symbolsOPLL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionIDA TAScellular_component
GO:0005589Collagen type VINAScellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005788Endoplasmic reticulum lumenTAScellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0022617Extracellular matrix disassemblyTASbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0030574Collagen catabolic processTASbiological_process
GO:0031012Extracellular matrixIDA ISScellular_component
GO:0042383SarcolemmaIEAcellular_component
GO:0043234Protein complexIPIcellular_component
GO:0048407Platelet-derived growth factor bindingIDAmolecular_function
GO:0070208Protein heterotrimerizationIPIbiological_process
GO:0071230Cellular response to amino acid stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09393010140.05415858440.64249849270.4383847786

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1015799400
GSE13712_SHEARDown-1.5942858083
GSE13712_STATICDown-0.9538297258
GSE19018Down-0.1940409984
GSE19899_A1Up0.0397032671
GSE19899_A2Up0.1104824157
PubMed_21979375_A1Up0.6830021507
PubMed_21979375_A2Down-0.0819029021
GSE35957Down-0.1927207988
GSE36640Down-0.8305101886
GSE54402Down-0.5821646697
GSE9593Up0.6277287832
GSE43922Down-0.0055300413
GSE24585Up0.2389230576
GSE37065Down-0.5468155250
GSE28863_A1Up0.8842398953
GSE28863_A2Up1.3428608192
GSE28863_A3Up0.9121616679
GSE28863_A4Down-0.0117240775
GSE48662Down-0.1663176975

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018149MicroarrayFunctional MTI (Weak)18185580
hsa-miR-1301-3pMIMAT0005797MIRT035972CLASHFunctional MTI (Weak)23622248
hsa-miR-877-3pMIMAT0004950MIRT037192CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039896CLASHFunctional MTI (Weak)23622248
hsa-miR-324-5pMIMAT0000761MIRT043222CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051548CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.