HCSGD entry for COL4A4
1. General information
| Official gene symbol | COL4A4 |
|---|---|
| Entrez ID | 1286 |
| Gene full name | collagen, type IV, alpha 4 |
| Other gene symbols | CA44 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005201 | Extracellular matrix structural constituent | IEA IMP | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005581 | Collagen | IEA | cellular_component |
| GO:0005587 | Collagen type IV | IDA | cellular_component |
| GO:0005605 | Basal lamina | IDA | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0022617 | Extracellular matrix disassembly | TAS | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0030574 | Collagen catabolic process | TAS | biological_process |
| GO:0032836 | Glomerular basement membrane development | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0835365602 | 0.7156800577 | 0.6087766381 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2324146695 |
| GSE13712_SHEAR | Up | 0.0149244490 |
| GSE13712_STATIC | Down | -0.0769324040 |
| GSE19018 | Up | 0.0622334484 |
| GSE19899_A1 | Up | 0.2083041051 |
| GSE19899_A2 | Up | 0.0118476103 |
| PubMed_21979375_A1 | Up | 0.3094201191 |
| PubMed_21979375_A2 | Up | 0.0375991124 |
| GSE35957 | Up | 3.6881661115 |
| GSE36640 | Up | 0.0513509347 |
| GSE54402 | Down | -0.1672818436 |
| GSE9593 | Down | -0.0134593391 |
| GSE43922 | Up | 0.0480284383 |
| GSE24585 | Down | -0.0423836771 |
| GSE37065 | Down | -0.0038444445 |
| GSE28863_A1 | Down | -0.1029472720 |
| GSE28863_A2 | Up | 0.0926047315 |
| GSE28863_A3 | Up | 0.0346735981 |
| GSE28863_A4 | Up | 0.0196400875 |
| GSE48662 | Up | 1.0160107966 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022562 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029341 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
