HCSGD entry for SYT2
1. General information
| Official gene symbol | SYT2 |
|---|---|
| Entrez ID | 127833 |
| Gene full name | synaptotagmin II |
| Other gene symbols | SytII |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005544 | Calcium-dependent phospholipid binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0007269 | Neurotransmitter secretion | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030666 | Endocytic vesicle membrane | TAS | cellular_component |
| GO:0030672 | Synaptic vesicle membrane | IEA | cellular_component |
| GO:0042584 | Chromaffin granule membrane | IEA | cellular_component |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6467674177 | 0.7367917556 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0873668518 |
| GSE13712_SHEAR | Up | 0.2884863551 |
| GSE13712_STATIC | Down | -0.0332363806 |
| GSE19018 | Up | 0.0371116632 |
| GSE19899_A1 | Up | 0.0197424519 |
| GSE19899_A2 | Up | 0.2107785812 |
| PubMed_21979375_A1 | Down | -0.3532370007 |
| PubMed_21979375_A2 | Down | -0.0430470214 |
| GSE35957 | Down | -0.1701231392 |
| GSE36640 | Up | 0.0658725918 |
| GSE54402 | Up | 0.0959733489 |
| GSE9593 | Up | 0.0045194000 |
| GSE43922 | Up | 0.0788377606 |
| GSE24585 | Up | 0.0515525531 |
| GSE37065 | Down | -0.0554659029 |
| GSE28863_A1 | Down | -0.0816051630 |
| GSE28863_A2 | Down | -0.1404629321 |
| GSE28863_A3 | Up | 0.2931636232 |
| GSE28863_A4 | Up | 0.1080678045 |
| GSE48662 | Down | -0.0117272219 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Botulinum Toxin Type B | DB00042 | BTD00070 | BIOD00070 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125b-2-3p | MIMAT0004603 | MIRT038632 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
