HCSGD entry for ADH4

1. General information

Official gene symbolADH4
Entrez ID127
Gene full namealcohol dehydrogenase 4 (class II), pi polypeptide
Other gene symbolsADH-2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001523Retinoid metabolic processIDAbiological_process
GO:0003960NADPH:quinone reductase activityISSmolecular_function
GO:0004022Alcohol dehydrogenase (NAD) activityIDAmolecular_function
GO:0004024Alcohol dehydrogenase activity, zinc-dependentIDAmolecular_function
GO:0004032Alditol:NADP+ 1-oxidoreductase activityIEAmolecular_function
GO:0004745Retinol dehydrogenase activityIDAmolecular_function
GO:0005503All-trans retinal bindingIDAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006066Alcohol metabolic processIDAbiological_process
GO:0006069Ethanol oxidationIDA TASbiological_process
GO:0006081Cellular aldehyde metabolic processIDAbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0008270Zinc ion bindingIDA IEAmolecular_function
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016491Oxidoreductase activityIEAmolecular_function
GO:0016620Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptorIDAmolecular_function
GO:0019115Benzaldehyde dehydrogenase activityIDAmolecular_function
GO:0019841Retinol bindingIDAmolecular_function
GO:0042572Retinol metabolic processIDAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046164Alcohol catabolic processISSbiological_process
GO:0051287NAD bindingIDAmolecular_function
GO:1901661Quinone metabolic processISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.21313574710.95977922190.88970696161.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0804750817
GSE13712_SHEARDown-0.0336955494
GSE13712_STATICUp0.0971205814
GSE19018Up0.1845377960
GSE19899_A1Down-0.0702864849
GSE19899_A2Up0.0492137981
PubMed_21979375_A1Down-0.2365077935
PubMed_21979375_A2Up0.1303215887
GSE35957Up0.1676482784
GSE36640Down-0.0100122087
GSE54402Up0.0018146584
GSE9593Down-0.0221873468
GSE43922Up0.0191952488
GSE24585Up0.1033518200
GSE37065Up0.0993013815
GSE28863_A1Up0.1219470466
GSE28863_A2Up1.2067992041
GSE28863_A3Up0.1976130338
GSE28863_A4Up0.0669390597
GSE48662Up0.1124068662

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527
CyclohexylformamideDB03559 EXPT01065

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.