HCSGD entry for CNN2
1. General information
| Official gene symbol | CNN2 |
|---|---|
| Entrez ID | 1265 |
| Gene full name | calponin 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001725 | Stress fiber | IDA | cellular_component |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005856 | Cytoskeleton | TAS | cellular_component |
| GO:0005911 | Cell-cell junction | TAS | cellular_component |
| GO:0007010 | Cytoskeleton organization | TAS | biological_process |
| GO:0010628 | Positive regulation of gene expression | IEA | biological_process |
| GO:0030097 | Hemopoiesis | IEA | biological_process |
| GO:0030336 | Negative regulation of cell migration | IEA | biological_process |
| GO:0031032 | Actomyosin structure organization | IEA | biological_process |
| GO:0032970 | Regulation of actin filament-based process | IDA | biological_process |
| GO:0042060 | Wound healing | IEA | biological_process |
| GO:0042127 | Regulation of cell proliferation | IEA | biological_process |
| GO:0050765 | Negative regulation of phagocytosis | IEA | biological_process |
| GO:0071260 | Cellular response to mechanical stimulus | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4821870674 | 0.0018921622 | 0.9999902473 | 0.0839858347 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.5083703231 |
| GSE13712_SHEAR | Down | -0.2435297772 |
| GSE13712_STATIC | Down | -0.1618762684 |
| GSE19018 | Down | -1.4118659628 |
| GSE19899_A1 | Down | -1.6082498467 |
| GSE19899_A2 | Down | -0.8409854836 |
| PubMed_21979375_A1 | Down | -1.3872801406 |
| PubMed_21979375_A2 | Down | -0.7941193798 |
| GSE35957 | Down | -0.0231942143 |
| GSE36640 | Down | -0.4920204336 |
| GSE54402 | Down | -0.7905211090 |
| GSE9593 | Down | -0.0968409255 |
| GSE43922 | Down | -0.7587321092 |
| GSE24585 | Up | 0.7668771389 |
| GSE37065 | Down | -1.0692221224 |
| GSE28863_A1 | Up | 1.2386650446 |
| GSE28863_A2 | Up | 0.2331865643 |
| GSE28863_A3 | Up | 0.2297382858 |
| GSE28863_A4 | Up | 0.0781773804 |
| GSE48662 | Up | 0.2324211492 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-133a-3p | MIMAT0000427 | MIRT021704 | Microarray | Functional MTI (Weak) | 21396852 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037661 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-346 | MIMAT0000773 | MIRT042725 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
