HCSGD entry for HSPB6
1. General information
| Official gene symbol | HSPB6 |
|---|---|
| Entrez ID | 126393 |
| Gene full name | heat shock protein, alpha-crystallin-related, B6 |
| Other gene symbols | Hsp20 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005212 | Structural constituent of eye lens | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006937 | Regulation of muscle contraction | IEA | biological_process |
| GO:0006950 | Response to stress | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4851401163 | 0.0082851867 | 0.9999902473 | 0.1821985798 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7874974408 |
| GSE13712_SHEAR | Down | -0.3223192295 |
| GSE13712_STATIC | Down | -0.5243440207 |
| GSE19018 | Up | 0.1556447480 |
| GSE19899_A1 | Down | -1.0677740209 |
| GSE19899_A2 | Up | 0.0288636353 |
| PubMed_21979375_A1 | Down | -1.6379270953 |
| PubMed_21979375_A2 | Down | -0.0719607098 |
| GSE35957 | Up | 2.3160907690 |
| GSE36640 | Down | -0.0328343573 |
| GSE54402 | Down | -1.7440736988 |
| GSE9593 | Up | 0.3052491576 |
| GSE43922 | Down | -1.2113684676 |
| GSE24585 | Down | -0.0237365720 |
| GSE37065 | Down | -0.5148117708 |
| GSE28863_A1 | Down | -0.0828688274 |
| GSE28863_A2 | Down | -0.1548677980 |
| GSE28863_A3 | Up | 0.2513463804 |
| GSE28863_A4 | Up | 0.2416936734 |
| GSE48662 | Up | 0.3535498262 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-320a | MIMAT0000510 | MIRT004508 | Luciferase reporter assay | Functional MTI | 19380620 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
