HCSGD entry for CNGB1

1. General information

Official gene symbolCNGB1
Entrez ID1258
Gene full namecyclic nucleotide gated channel beta 1
Other gene symbolsCNCG2 CNCG3L CNCG4 CNG4 CNGB1B GAR1 GARP RCNC2 RCNCb RCNCbeta RP45
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005222Intracellular cAMP activated cation channel activityIEAmolecular_function
GO:0005223Intracellular cGMP activated cation channel activityIBA IEAmolecular_function
GO:0005249Voltage-gated potassium channel activityIBAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneIBAcellular_component
GO:0006810TransportTASbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0007603Phototransduction, visible lightTASbiological_process
GO:0007608Sensory perception of smellIEAbiological_process
GO:0015276Ligand-gated ion channel activityTASmolecular_function
GO:0016056Rhodopsin mediated signaling pathwayTASbiological_process
GO:0017071Intracellular cyclic nucleotide activated cation channel complexIEAcellular_component
GO:0022400Regulation of rhodopsin mediated signaling pathwayTASbiological_process
GO:0030552CAMP bindingIEAmolecular_function
GO:0030553CGMP bindingIBAmolecular_function
GO:0034765Regulation of ion transmembrane transportIBAbiological_process
GO:0042391Regulation of membrane potentialIBAbiological_process
GO:0043195Terminal boutonIEAcellular_component
GO:0051049Regulation of transportIBAbiological_process
GO:0051290Protein heterotetramerizationIEAbiological_process
GO:0051480Cytosolic calcium ion homeostasisIEAbiological_process
GO:0071805Potassium ion transmembrane transportIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81882425060.60284108130.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0195161241
GSE13712_SHEARUp0.0652214829
GSE13712_STATICDown-0.1245401113
GSE19018Up0.1308880057
GSE19899_A1Down-0.0954999405
GSE19899_A2Up0.1266149647
PubMed_21979375_A1Up0.0265011285
PubMed_21979375_A2Down-0.1290791337
GSE35957Up0.1518575436
GSE36640Up0.0684797258
GSE54402Up0.0393837211
GSE9593Down-0.0663304949
GSE43922Down-0.0017494034
GSE24585Down-0.1759126643
GSE37065Down-0.0577591508
GSE28863_A1Down-0.2804516976
GSE28863_A2Down-0.0465360257
GSE28863_A3Up0.2938389914
GSE28863_A4Down-0.0025150394
GSE48662Up0.2045801303

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017103MicroarrayFunctional MTI (Weak)18185580
hsa-miR-125b-5pMIMAT0000423MIRT045902CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.