HCSGD entry for ABCC2

1. General information

Official gene symbolABCC2
Entrez ID1244
Gene full nameATP-binding cassette, sub-family C (CFTR/MRP), member 2
Other gene symbolsABC30 CMOAT DJS MRP2 cMRP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006200ATP catabolic processTASbiological_process
GO:0006810TransportTASbiological_process
GO:0006855Drug transmembrane transportIEAbiological_process
GO:0006979Response to oxidative stressIEAbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0008514Organic anion transmembrane transporter activityTASmolecular_function
GO:0009408Response to heatIEAbiological_process
GO:0015732Prostaglandin transportIEAbiological_process
GO:0016324Apical plasma membraneISScellular_component
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0030644Cellular chloride ion homeostasisIEAbiological_process
GO:0031427Response to methotrexateIEAbiological_process
GO:0034220Ion transmembrane transportTASbiological_process
GO:0042626ATPase activity, coupled to transmembrane movement of substancesIEAmolecular_function
GO:0043627Response to estrogenIEAbiological_process
GO:0046581Intercellular canaliculusIEAcellular_component
GO:0046685Response to arsenic-containing substanceIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0070327Thyroid hormone transportIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51384456900.79412675810.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0225069831
GSE13712_SHEARUp0.1685029904
GSE13712_STATICDown-0.2332791732
GSE19018Up0.0209865488
GSE19899_A1Down-0.0257377415
GSE19899_A2Down-0.0710022003
PubMed_21979375_A1Up0.0177867371
PubMed_21979375_A2Up0.0208372422
GSE35957Down-0.1529931489
GSE36640Up0.1415429939
GSE54402Up0.2246734965
GSE9593Up0.1341148102
GSE43922Up0.1336450015
GSE24585Down-0.3816970061
GSE37065Up0.1421701515
GSE28863_A1Up0.1009456234
GSE28863_A2Up0.1978013165
GSE28863_A3Up0.0369608370
GSE28863_A4Up0.1303026267
GSE48662Down-0.1215697885

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Adenosine triphosphateDB00171 NUTR00017 | EXPT00007
SulfinpyrazoneDB01138 APRD00620

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.