HCSGD entry for NOXO1
1. General information
| Official gene symbol | NOXO1 |
|---|---|
| Entrez ID | 124056 |
| Gene full name | NADPH oxidase organizer 1 |
| Other gene symbols | P41NOX P41NOXA P41NOXB P41NOXC SH3PXD5 SNX28 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005543 | Phospholipid binding | TAS | molecular_function |
| GO:0006801 | Superoxide metabolic process | IEA | biological_process |
| GO:0007154 | Cell communication | IEA | biological_process |
| GO:0010310 | Regulation of hydrogen peroxide metabolic process | TAS | biological_process |
| GO:0016176 | Superoxide-generating NADPH oxidase activator activity | TAS | molecular_function |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0022617 | Extracellular matrix disassembly | IMP | biological_process |
| GO:0035091 | Phosphatidylinositol binding | IEA | molecular_function |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0043020 | NADPH oxidase complex | IDA | cellular_component |
| GO:0043085 | Positive regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
| GO:0060263 | Regulation of respiratory burst | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7519797234 | 0.5489226853 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0526958700 |
| GSE13712_SHEAR | Up | 0.0057562415 |
| GSE13712_STATIC | Down | -0.1054359326 |
| GSE19018 | Up | 0.0159193807 |
| GSE19899_A1 | Down | -0.0827321485 |
| GSE19899_A2 | Up | 0.0426209327 |
| PubMed_21979375_A1 | Down | -0.0567406264 |
| PubMed_21979375_A2 | Down | -0.1791470499 |
| GSE35957 | Up | 0.0029284794 |
| GSE36640 | Down | -0.1517556293 |
| GSE54402 | Down | -0.0119542243 |
| GSE9593 | Down | -0.0339929777 |
| GSE43922 | Up | 0.1246453752 |
| GSE24585 | Up | 0.0443258309 |
| GSE37065 | Down | -0.1213120330 |
| GSE28863_A1 | Down | -0.0317385657 |
| GSE28863_A2 | Down | -0.2360697017 |
| GSE28863_A3 | Up | 0.3379441561 |
| GSE28863_A4 | Up | 0.1448595361 |
| GSE48662 | Down | -0.0636817658 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Ecabet | DB05265 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024910 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026699 | Microarray | Functional MTI (Weak) | 19074876 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
