HCSGD entry for CCR6

1. General information

Official gene symbolCCR6
Entrez ID1235
Gene full namechemokine (C-C motif) receptor 6
Other gene symbolsBN-1 C-C CKR-6 CC-CKR-6 CCR-6 CD196 CKR-L3 CKRL3 CMKBR6 DCR2 DRY6 GPR29 GPRCY4 STRL22
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002407Dendritic cell chemotaxisTASbiological_process
GO:0004872Receptor activityTASmolecular_function
GO:0004950Chemokine receptor activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006928Cellular component movementTASbiological_process
GO:0006935ChemotaxisTASbiological_process
GO:0006955Immune responseTASbiological_process
GO:0006959Humoral immune responseTASbiological_process
GO:0006968Cellular defense responseTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationTASbiological_process
GO:0016493C-C chemokine receptor activityIEAmolecular_function
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0070098Chemokine-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.88032102880.46669148970.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0981318341
GSE13712_SHEARUp0.0200231051
GSE13712_STATICDown-0.1501160418
GSE19018Up0.0413441289
GSE19899_A1Down-0.0263957749
GSE19899_A2Down-0.2935307633
PubMed_21979375_A1Up0.0039698545
PubMed_21979375_A2Down-0.1208492241
GSE35957Up0.0929782150
GSE36640Up0.0229529129
GSE54402Down-0.0718411920
GSE9593Down-0.1352528479
GSE43922Up0.0050151692
GSE24585Up0.0016177933
GSE37065Down-0.0485175303
GSE28863_A1Down-0.1342184109
GSE28863_A2Down-0.0911194297
GSE28863_A3Up0.1586871800
GSE28863_A4Up0.0564139649
GSE48662Up0.1797161937

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029835MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.