HCSGD entry for SOCS4
1. General information
| Official gene symbol | SOCS4 |
|---|---|
| Entrez ID | 122809 |
| Gene full name | suppressor of cytokine signaling 4 |
| Other gene symbols | SOCS7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0007175 | Negative regulation of epidermal growth factor-activated receptor activity | IDA | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0032436 | Positive regulation of proteasomal ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0040008 | Regulation of growth | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1274463926 | 0.7622897534 | 0.7269485170 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1760787511 |
| GSE13712_SHEAR | Up | 0.5259254554 |
| GSE13712_STATIC | Down | -0.1215842456 |
| GSE19018 | Down | -0.8383140263 |
| GSE19899_A1 | Up | 0.1859329172 |
| GSE19899_A2 | Down | -0.0826324732 |
| PubMed_21979375_A1 | Up | 0.2840451112 |
| PubMed_21979375_A2 | Down | -0.0218073408 |
| GSE35957 | Up | 0.4637351551 |
| GSE36640 | Up | 0.2682256592 |
| GSE54402 | Up | 0.3956330618 |
| GSE9593 | Down | -0.0029010588 |
| GSE43922 | Up | 0.1026391046 |
| GSE24585 | Up | 0.1158168749 |
| GSE37065 | Up | 0.1452977198 |
| GSE28863_A1 | Up | 0.2624007725 |
| GSE28863_A2 | Up | 0.2288886892 |
| GSE28863_A3 | Down | -0.6051973138 |
| GSE28863_A4 | Up | 0.1429831575 |
| GSE48662 | Down | -0.1834376309 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT005326 | Luciferase reporter assay//Northern blot//qRT-PCR//Western blot//Reporter assay;Western blot;qRT-PCR;Other | Functional MTI | 20486857 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020274 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025579 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031056 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031212 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040330 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
