HCSGD entry for SPIC


1. General information

Official gene symbolSPIC
Entrez ID121599
Gene full nameSpi-C transcription factor (Spi-1/PU.1 related)
Other gene symbolsSPI-C
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001824Blastocyst developmentIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81312564110.59517604190.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0736354523
GSE13712_SHEARDown-0.0214336899
GSE13712_STATICUp0.0532273039
GSE19018Up0.0619118892
GSE19899_A1Up0.0549043900
GSE19899_A2Down-0.0246369336
PubMed_21979375_A1Up0.0388569233
PubMed_21979375_A2Up0.0784426139
GSE35957Up0.1603814407
GSE36640Up0.0057191364
GSE54402Down-0.0168911112
GSE9593Down-0.0265968702
GSE43922Down-0.1576885076
GSE24585Down-0.5385607314
GSE37065Down-0.0335907019
GSE28863_A1Down-0.0116534659
GSE28863_A2Down-0.0024628662
GSE28863_A3Up0.0723909434
GSE28863_A4Up0.0362743038
GSE48662Up0.0799007237

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018368MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.