HCSGD entry for SP7

1. General information

Official gene symbolSP7
Entrez ID121340
Gene full nameSp7 transcription factor
Other gene symbolsOI11 OI12 OSX osterix
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001649Osteoblast differentiationIDA IEA ISSbiological_process
GO:0003677DNA bindingIEA ISSmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterIEA ISSbiological_process
GO:0017151DEAD/H-box RNA helicase bindingIEA ISSmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0060218Hematopoietic stem cell differentiationIDAbiological_process
GO:2000738Positive regulation of stem cell differentiationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.77981499560.64845593250.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0473897317
GSE13712_SHEARDown-0.1250982395
GSE13712_STATICDown-0.1544796180
GSE19018Down-0.1240799229
GSE19899_A1Down-0.0077808325
GSE19899_A2Up0.1054414976
PubMed_21979375_A1Up0.2081640139
PubMed_21979375_A2Up0.2047342331
GSE35957Up0.2501985570
GSE36640Up0.0661857528
GSE54402Down-0.0817806277
GSE9593Down-0.0611795784
GSE43922Up0.1797730833
GSE24585Down-0.0088895505
GSE37065Down-0.0401002274
GSE28863_A1Down-0.3413505538
GSE28863_A2Down-0.1417708037
GSE28863_A3Up0.2618129913
GSE28863_A4Up0.0004694794
GSE48662Up0.0337198477

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-135b-5pMIMAT0000758MIRT004567qRT-PCRFunctional MTI (Weak)19795981
hsa-miR-7-5pMIMAT0000252MIRT025634MicroarrayFunctional MTI (Weak)17612493
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.