HCSGD entry for CLTB
1. General information
| Official gene symbol | CLTB |
|---|---|
| Entrez ID | 1212 |
| Gene full name | clathrin, light chain B |
| Other gene symbols | LCB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005802 | Trans-Golgi network | IEA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0030118 | Clathrin coat | ISS NAS | cellular_component |
| GO:0030130 | Clathrin coat of trans-Golgi network vesicle | IEA | cellular_component |
| GO:0030132 | Clathrin coat of coated pit | IEA | cellular_component |
| GO:0042277 | Peptide binding | IEA | molecular_function |
| GO:0060170 | Ciliary membrane | IEA | cellular_component |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0360193572 | 0.9435811291 | 0.4316536331 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4919971522 |
| GSE13712_SHEAR | Up | 0.1777828783 |
| GSE13712_STATIC | Up | 0.2066317587 |
| GSE19018 | Up | 0.0090963032 |
| GSE19899_A1 | Down | -0.0341091725 |
| GSE19899_A2 | Up | 0.6189348290 |
| PubMed_21979375_A1 | Up | 0.7808473297 |
| PubMed_21979375_A2 | Up | 0.3373728454 |
| GSE35957 | Up | 0.0316764327 |
| GSE36640 | Up | 1.1855353891 |
| GSE54402 | Down | -0.1384942807 |
| GSE9593 | Up | 0.3001463860 |
| GSE43922 | Up | 0.1521746457 |
| GSE24585 | Up | 0.7607726173 |
| GSE37065 | Down | -0.0085631100 |
| GSE28863_A1 | Down | -0.5327680534 |
| GSE28863_A2 | Up | 0.0316831266 |
| GSE28863_A3 | Down | -0.2018458451 |
| GSE28863_A4 | Down | -0.0410492134 |
| GSE48662 | Up | 0.3454269764 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025306 | Proteomics | Functional MTI (Weak) | 21566225 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 10998569 | A specific characteristic of CNS gangliosides is the structure of their long-chain base (LCB) |
| 10998569 | In fact, considering all the mammalian cell sphingolipids, gangliosides, sulphatides, neutral glycosphingolipids, sphingomyelin and ceramides, it would seem that while the LCB with 18 carbons is the main component of all sphingolipids, only CNS gangliosides contain significant amounts of LCB with 20 carbons |
| 10998569 | In this review we discuss the chemistry, physico-chemistry and metabolism of ganglioside species differing in LCB length and introduce the hypothesis that the varying ratio between C18- and C20-gangliosides during CNS development and aging can be instrumental in modulating membrane domain organisation and cell properties |
Entries Per Page
Displaying Page of
