HCSGD entry for CLN5

1. General information

Official gene symbolCLN5
Entrez ID1203
Gene full nameceroid-lipofuscinosis, neuronal 5
Other gene symbolsNCL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005537Mannose bindingIDAmolecular_function
GO:0005764LysosomeIDAcellular_component
GO:0005765Lysosomal membraneIDAcellular_component
GO:0005775Vacuolar lumenIEAcellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0006465Signal peptide processingIDAbiological_process
GO:0007042Lysosomal lumen acidificationIMPbiological_process
GO:0007420Brain developmentIEPbiological_process
GO:0007601Visual perceptionIEAbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0016021Integral component of membraneIDA NAScellular_component
GO:0022008NeurogenesisIEPbiological_process
GO:0030163Protein catabolic processNASbiological_process
GO:0042551Neuron maturationNASbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0070085GlycosylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00607015310.99455328070.20581812341.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5902053810
GSE13712_SHEARUp0.4673025125
GSE13712_STATICUp0.4475160951
GSE19018Down-0.0905827882
GSE19899_A1Up0.2021735951
GSE19899_A2Up0.6629760304
PubMed_21979375_A1Up0.4846658660
PubMed_21979375_A2Up0.5624234923
GSE35957Up0.4390466045
GSE36640Up1.2826052908
GSE54402Down-0.4236240895
GSE9593Up0.5868515264
GSE43922Up0.5219870249
GSE24585Up0.1758568204
GSE37065Up0.1415049966
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.4736092847

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022416MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.