HCSGD entry for ADD2
1. General information
| Official gene symbol | ADD2 |
|---|---|
| Entrez ID | 119 |
| Gene full name | adducin 2 (beta) |
| Other gene symbols | ADDB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | TAS | molecular_function |
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006461 | Protein complex assembly | IDA | biological_process |
| GO:0008290 | F-actin capping protein complex | IDA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016023 | Cytoplasmic membrane-bounded vesicle | IDA | cellular_component |
| GO:0030036 | Actin cytoskeleton organization | IC | biological_process |
| GO:0030097 | Hemopoiesis | IEA | biological_process |
| GO:0030507 | Spectrin binding | IDA | molecular_function |
| GO:0032092 | Positive regulation of protein binding | IDA | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0051015 | Actin filament binding | IDA | molecular_function |
| GO:0051016 | Barbed-end actin filament capping | IDA | biological_process |
| GO:0051017 | Actin filament bundle assembly | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4843216101 | 0.6083429277 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0156366584 |
| GSE13712_SHEAR | Down | -0.0453388217 |
| GSE13712_STATIC | Down | -0.0561445381 |
| GSE19018 | Up | 0.1780027428 |
| GSE19899_A1 | Up | 0.1436886492 |
| GSE19899_A2 | Up | 0.2157402095 |
| PubMed_21979375_A1 | Up | 0.0153161899 |
| PubMed_21979375_A2 | Down | -0.0849423084 |
| GSE35957 | Up | 0.2587926679 |
| GSE36640 | Down | -0.0033117854 |
| GSE54402 | Up | 0.0687228336 |
| GSE9593 | Down | -0.0348392707 |
| GSE43922 | Up | 0.1865079653 |
| GSE24585 | Down | -0.9815308841 |
| GSE37065 | Down | -0.1343205689 |
| GSE28863_A1 | Up | 0.3215297978 |
| GSE28863_A2 | Up | 0.1554389037 |
| GSE28863_A3 | Up | 0.2386882182 |
| GSE28863_A4 | Down | -0.0964780379 |
| GSE48662 | Up | 0.0354879045 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1301-3p | MIMAT0005797 | MIRT035978 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-107 | MIMAT0000104 | MIRT048288 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
