HCSGD entry for PIK3AP1

1. General information

Official gene symbolPIK3AP1
Entrez ID118788
Gene full namephosphoinositide-3-kinase adaptor protein 1
Other gene symbolsBCAP RP11-34E5.3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005829CytosolISS TAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0014068Positive regulation of phosphatidylinositol 3-kinase signalingISSbiological_process
GO:0016020MembraneISScellular_component
GO:0034122Negative regulation of toll-like receptor signaling pathwayIEAbiological_process
GO:0034123Positive regulation of toll-like receptor signaling pathwayIEAbiological_process
GO:0034134Toll-like receptor 2 signaling pathwayISSbiological_process
GO:0034142Toll-like receptor 4 signaling pathwayISSbiological_process
GO:0034154Toll-like receptor 7 signaling pathwayISSbiological_process
GO:0034162Toll-like receptor 9 signaling pathwayISSbiological_process
GO:0036312Phosphatidylinositol 3-kinase regulatory subunit bindingISSmolecular_function
GO:0042802Identical protein bindingIEAmolecular_function
GO:0050727Regulation of inflammatory responseISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85413522660.56346816610.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0705843621
GSE13712_SHEARUp0.0917043630
GSE13712_STATICDown-0.0527277681
GSE19018Down-0.3599139411
GSE19899_A1Down-0.0949077023
GSE19899_A2Up0.0525734509
PubMed_21979375_A1Down-0.0777416910
PubMed_21979375_A2Up0.0589624335
GSE35957Up0.1273387719
GSE36640Down-0.1344524995
GSE54402Up0.0395969200
GSE9593Up0.0032996690
GSE43922Up0.0998852858
GSE24585Down-0.1003083663
GSE37065Up0.1873314822
GSE28863_A1Down-0.2292832536
GSE28863_A2Down-0.1580074852
GSE28863_A3Up0.2150751387
GSE28863_A4Up0.1125560165
GSE48662Down-0.0596551176

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-106b-5pMIMAT0000680MIRT044289CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.