HCSGD entry for CLCN6
1. General information
| Official gene symbol | CLCN6 |
|---|---|
| Entrez ID | 1185 |
| Gene full name | chloride channel, voltage-sensitive 6 |
| Other gene symbols | CLC-6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005247 | Voltage-gated chloride channel activity | IEA NAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005765 | Lysosomal membrane | IDA | cellular_component |
| GO:0006821 | Chloride transport | NAS | biological_process |
| GO:0006884 | Cell volume homeostasis | NAS | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0009612 | Response to mechanical stimulus | IEA | biological_process |
| GO:0010008 | Endosome membrane | TAS | cellular_component |
| GO:0015297 | Antiporter activity | IEA | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0034765 | Regulation of ion transmembrane transport | NAS | biological_process |
| GO:0044070 | Regulation of anion transport | NAS | biological_process |
| GO:0051049 | Regulation of transport | NAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:1902476 | Chloride transmembrane transport | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2937413890 | 0.6129324684 | 0.9939623988 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2796544534 |
| GSE13712_SHEAR | Down | -0.2127961068 |
| GSE13712_STATIC | Down | -0.2314573445 |
| GSE19018 | Up | 0.0257466457 |
| GSE19899_A1 | Down | -0.0649828860 |
| GSE19899_A2 | Up | 0.1472259672 |
| PubMed_21979375_A1 | Down | -0.4380913074 |
| PubMed_21979375_A2 | Up | 0.3536649115 |
| GSE35957 | Down | -0.1755173300 |
| GSE36640 | Up | 0.4395962474 |
| GSE54402 | Down | -0.0743195449 |
| GSE9593 | Up | 0.1140023437 |
| GSE43922 | Down | -0.1745004882 |
| GSE24585 | Up | 0.0388085955 |
| GSE37065 | Down | -0.1001891268 |
| GSE28863_A1 | Up | 0.3241819899 |
| GSE28863_A2 | Up | 0.7373525319 |
| GSE28863_A3 | Down | -0.0035137770 |
| GSE28863_A4 | Down | -0.0867350687 |
| GSE48662 | Up | 0.1437854042 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017686 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046450 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
