HCSGD entry for CLCN4

1. General information

Official gene symbolCLCN4
Entrez ID1183
Gene full namechloride channel, voltage-sensitive 4
Other gene symbolsCLC4 ClC-4 ClC-4A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005216Ion channel activityIEAmolecular_function
GO:0005247Voltage-gated chloride channel activityIEAmolecular_function
GO:0005254Chloride channel activityIDAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0006810TransportTASbiological_process
GO:0006821Chloride transportIDAbiological_process
GO:0010008Endosome membraneTAScellular_component
GO:0015297Antiporter activityIEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0030554Adenyl nucleotide bindingIEAmolecular_function
GO:0031901Early endosome membraneIEAcellular_component
GO:0031902Late endosome membraneIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034765Regulation of ion transmembrane transportTASbiological_process
GO:0044070Regulation of anion transportTASbiological_process
GO:0051049Regulation of transportTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:1902476Chloride transmembrane transportIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81400840770.06597499340.99999024730.4849281765

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1063776559
GSE13712_SHEARDown-0.3513361668
GSE13712_STATICDown-0.2090932088
GSE19018Up0.2456839672
GSE19899_A1Up0.0038642272
GSE19899_A2Up0.0505900240
PubMed_21979375_A1Down-0.4468922733
PubMed_21979375_A2Up0.0355280745
GSE35957Down-0.2881280029
GSE36640Up0.0341695425
GSE54402Down-0.4605032704
GSE9593Down-0.1773914360
GSE43922Down-0.2567305756
GSE24585Down-1.4941080164
GSE37065Up0.1820089745
GSE28863_A1Down-0.2304972467
GSE28863_A2Up0.4548701322
GSE28863_A3Up0.0463061585
GSE28863_A4Up0.0684054413
GSE48662Up0.1560776921

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.