HCSGD entry for AP3S1
1. General information
| Official gene symbol | AP3S1 |
|---|---|
| Entrez ID | 1176 |
| Gene full name | adaptor-related protein complex 3, sigma 1 subunit |
| Other gene symbols | CLAPS3 Sigma3A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005215 | Transporter activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0008089 | Anterograde axon cargo transport | ISS | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | TAS | biological_process |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0030117 | Membrane coat | IEA | cellular_component |
| GO:0030119 | AP-type membrane coat adaptor complex | TAS | cellular_component |
| GO:0030123 | AP-3 adaptor complex | IDA | cellular_component |
| GO:0030133 | Transport vesicle | TAS | cellular_component |
| GO:0030659 | Cytoplasmic vesicle membrane | IEA | cellular_component |
| GO:0048490 | Anterograde synaptic vesicle transport | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8482390601 | 0.2245106759 | 0.9999902473 | 0.9118785538 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0261492950 |
| GSE13712_SHEAR | Down | -0.0690744611 |
| GSE13712_STATIC | Up | 0.0298340136 |
| GSE19018 | Up | 0.3315138355 |
| GSE19899_A1 | Down | -0.2408942486 |
| GSE19899_A2 | Down | -0.1109077129 |
| PubMed_21979375_A1 | Down | -0.1425164577 |
| PubMed_21979375_A2 | Down | -0.2937637308 |
| GSE35957 | Up | 0.0066632013 |
| GSE36640 | Up | 0.0967881545 |
| GSE54402 | Down | -0.2804974844 |
| GSE9593 | Up | 0.2575313089 |
| GSE43922 | Down | -0.1804293981 |
| GSE24585 | Down | -0.2360781035 |
| GSE37065 | Up | 0.1416130147 |
| GSE28863_A1 | Up | 0.2604604888 |
| GSE28863_A2 | Up | 0.4188463815 |
| GSE28863_A3 | Down | -0.2289607549 |
| GSE28863_A4 | Down | -0.1560932667 |
| GSE48662 | Down | -0.3682386376 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028680 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037232 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-2-3p | MIMAT0004550 | MIRT038700 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040959 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
